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Treatment with 0.5 to 2 × 10 −5 M dopamine induced cell cycle arrest and apoptosis in rapidly dividing B-cells via oxidative stress (Meredith et al., 2006), and in peripheral blood lymphocytes (PBLs), 1 to 5 × 10 −4 M dopamine induced intracellular ROS levels and apoptotic cell death through oxidative stress